This junction is north of Rutherglen station. The line from Rutherglen West Junction, to the south west, and Rutherglen Central Junction, to the south east, meet here. To the north the line crosses the River Clyde.
The present junction essentially replaces the earlier Clydebridge Junction which was further north, directly south of the River Clyde.
To the south the double track Rutherglen Central Junction curve passes round the island platform of Rutherglen station.
The former Rutherglen North Junction [1st] was at the north end of earlier version of Rutherglen station, Rutherglen [3rd].